They demonstrate that the mesenchymal stem cells that support the tumor favor the expansion of the most aggressive cancer stem cells

An international team of scientists demonstrates that growth factors and proteins (cytokines) released by mesenchymal stem cells surrounding the tumor favor the selection of cancer stem cells (CMCs) with specific chromosomal alterations that make them more aggressive.

A team of scientists made up of researchers from different national and international institutions, and led by the University of Granada, has demonstrated for the first time that growth factors and proteins (cytokines) released by mesenchymal stem cells (MSC) that surround the tumor allows you to select and increase cancer stem cells (CMCs) with chromosomal alterations that make them more aggressive and resistant to treatment.

MSCs are a type of stem cells, present in a wide variety of tissues (bone marrow, blood and umbilical cord tissue, skin, fatty or muscle tissue...) and capable of producing different specialized cells found in the body's tissues. human. For example, they can differentiate (or specialize) into cartilage cells (chondrocytes), bone cells (osteoblasts), and fat cells (adipocytes).